MLB: Cincinnati Reds vs San Diego Padres odds, picks, and predictions

At 9:40 p.m. ET on Tuesday, the Cincinnati Reds (2-9) and San Diego Padres (7-5) face off in the middle game of a three-game series at Petco Park. Let's look at the odds for the Reds vs. Padres matchup with MLB picks and predictions. After a 4-1 victory in the season opener on Monday, San Diego is up 1-0. Cincinnati is 0-7 in its last seven games, with an OPS below.600. In the last two seasons, the Padres have gone 7-1 versus the Reds (2021-22). During that time, the Friars have allowed just 3.50 runs per game.

Cincinnati Reds vs San Diego Padres: Projected starters

Reiver Sanmartin (LHP) vs. Joe Musgrove (RHP)

Sanmartin makes his second start (0-1, 6.14 ERA). Through 7 1/3 innings, he has a 1.50 WHIP, 6.1 BB/9, and 4.9 K/9. Musgrove (1-0, 1.42 ERA) will make his third start of the season. Through 12 2/3 innings, he has a 0.71 WHIP, 0.0 BB/9, and 10.0 K/9.

Cincinnati Reds vs San Diego Padres picks and predictions

Prediction: Reds 5, Padres 4